Top Vacation Rentals in South Carolina Lowcountry ᐅ Instant booking

We found 6,859 accommodations in

South Carolina

South Carolina Lowcountry

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Popular destinations

Vacation house for 4 people, with terrace, with pets - 1

Adorable Classic 2 Br Cottage~ Cooper Cottage

550 yd to the beach

Sleeps 4 pers.3 bedrooms592 ft²

TerraceParkingKitchenInternet

Renovated and walking distance to Downtown

Sleeps 2 pers.1 bedroom581 ft²

ParkingInternet

One more unit available

Secure dataPowered by HoliduReliable service

Second Floor Ocean View- Steps from the Beach! 1 Bedroom villa in a gated Resort

300 yd to the beach

Sleeps 2 pers.1 bedroom538 ft²

PoolBalconyParkingInternet

The Sleepy Shack - Private, Cozy Cottage for your next getaway!

8.6 mi to the beach

Sleeps 3 pers.1 bedroom344 ft²

TerraceParkingInternet

Seawatch Island Club

250 yd to the beach

Sleeps 6 pers.2 bedrooms

PoolBalconyParkingKitchen

Players Club Resort

4.7 mi to the beach

Sleeps 6 pers.2 bedrooms

PoolBalconyYardParking

Bright and Spacious Downtown Condo

9 mi to the beach

Sleeps 6 pers.2 bedrooms

The Bungalow - Charming 2 Bed/2 Bath Guest House on 2 acres in Summerville, Sc

Sleeps 4 pers.2 bedrooms990 ft²

YardTerraceParkingInternet

Waterfront Gem in the heart of James Island!

4.2 mi to the beach

Sleeps 5 pers.2 bedrooms

BalconyYardParkingInternet

Cottage in the Oaks is a restored Historical Cottage from the late 1800’s

Sleeps 4 pers.1 bedroom

YardTerraceParkingInternet

Charming Coastal Casa on Beaufort's Battery Creek

3.2 mi to the beach

Sleeps 4 pers.1 bedroom581 ft²

TerraceParkingInternet

Historic Home 2 Blocks To King, Backyard Patio

8.9 mi to the beach

Sleeps 6 pers.3 bedrooms980 ft²

BalconyYardParkingInternet

Historic Home Located in historic district of Beaufort, Sc

Sleeps 6 pers.2 bedrooms1,044 ft²

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Adorable Classic 2 Br Cottage~ Cooper Cottage

Renovated and walking distance to Downtown

Staybridge Charleston - Mount Pleasant

Relaxing resort home, newly renovated

Hotel Ryder

Charleston Studio Cottage minutes from Historic Downtown with offstreet parking

Players Club Resort

Shared pool, three bedroom ground level apartment~ Folly Cottage

Restored servants' quarters for 1812 house in heart of Historic District

Emeline Hotel

Hank's Loft

Luxury Charleston Waterfront Getaway

Modern Charleston Getaway

Oceanfront 1Br/1Ba Condo~Host on the Coast

Water Front Edisto with Private Dock \non Deep Creek overlooking the Ocean

Ocean View at Island Club

1 Bedroom Cottage in the Old Historic District. Free Street Parking.

Ocean View at Island Club

Seawatch Island Club

Second Floor Ocean View- Steps from the Beach! 1 Bedroom villa in a gated Resort

The Sleepy Shack - Private, Cozy Cottage for your next getaway!

Seawatch Island Club

Players Club Resort

Bright and Spacious Downtown Condo

The Bungalow - Charming 2 Bed/2 Bath Guest House on 2 acres in Summerville, Sc

Waterfront Gem in the heart of James Island!

Cottage in the Oaks is a restored Historical Cottage from the late 1800’s

Charming Coastal Casa on Beaufort's Battery Creek

Historic Home 2 Blocks To King, Backyard Patio

Historic Home Located in historic district of Beaufort, Sc